Thalassemia: Symptoms, Causes and Prevention

We know, hemoglobin is the most important protein molecule in our red blood cells that carries oxygen to all parts of the body. This highly important substance is the targeted cause of the thalassemia.

Thalassemia, an inherited blood disorder is the result of an unusual form of hemoglobin and then the excessive destruction of red blood cells. It is actually caused by either a genetic mutation or a deletion of certain key gene fragments.

Symptoms of thalassemia

Symptoms are not visible always. They appear obvious with rising age and according to the types of thalassemia. Some common symptoms of thalassemia are-

  • Fatigue, weakness, chest pain, shortness of breath, leg cramps, rapid heartbeat, headaches
  • Dark urine, yellow or pale skin (jaundice)
  • Bone deformities (In the face particularly), slow growth and development, abdominal swelling, poor feeding, abnormal bleeding

Skeletal deformities may result in an excessive production of bone marrow. A serious complication of this disorder that, it can lead to organ failure.

Thalassemia: Types, Diagnosis, and Treatment

What are the chances of getting Thalassemia?

Thalassemia occurs particularly when there is a deformity in one of the genes participating in hemoglobin production. People who have only single gene affected do not show any symptoms. It mostly obtains from parents so it called an inherited disorder.

Single gene infected is simply meant only one of the parents is a carrier for thalassemia and is known as thalassemia minor. It probably does not show any symptoms of this type but a person is a carrier of the disease.

If in case, both parents are carriers of thalassemia then you are at greater risk of inheriting the serious form of it. The mutations associated with thalassemia are passed from parents to children.

As we learned thalassemia disrupts normal mutations in the DNA that produces hemoglobin causes anemia. It eventually leaves your body starved for oxygen and you fatigued.

The Prevention

Thalassemia, which is not serious, may not require treatment but serious type of this disorder require treatment like a regular blood transfusion. Complications vary in this disorder and possible few are contracting hepatitis A or B, bone deformities heart problems, diabetes-like severe difficulties.

It requires constant medical care to control this condition effectively. A person with thalassemia need to take precautions as follows-

  • It is always important to be aware of any disorder or any abnormality in health. Thalassemia is an incurable disease, therefore, it needs prevention.
  • If you find any such symptoms or planning for a baby (for gene carriers) keep in touch with your genetic counselor
  • Blood transfusion receiver strictly follow their transfusion and chelation schedule
  • They should attend their regular appointments with their physicist
  • Try to keep your attitude positive
  • Follow a healthy diet
  • Stay tuned for your daily exercises
  • Avoid taking iron-rich food
  • Keep vaccination up to date to prevent illness (More important for those who receive blood transfusion)
  • A continuous education model for medical staff is required
  • The government must motivate gynecologists and pathologies to ensure every pregnant woman goes through the HbA2 test before week 14 of pregnancy

Thalassemia is becoming one of the serious and incurable inherited disorder since around 1 lakh newborns are born with a severe type of thalassemia every year.

Grab E-Books

Master Your Mind

Develop your mindset so that you can achieve greater success in your life

Road Untaken

Discover how to get out of your comfort zone to finally accomplish your goals and reach new heights.

You'll Also Like

The blood group A is at a higher risk of COVID-19, study says

Is there a relationship between the blood type and the Coronavirus Infection susceptibility? The research showed that the blood group A is at a...

Blood Transfusions are vital to saving lives.

Before the discovery of ABO blood types by Karl Landsteiner in 1900 doctors experimented many random transfusions to save lives. In a very first...

Thalassemia: Types, Diagnosis and Treatment

Thalassemia is an inherited blood disorder that disrupts hemoglobin production which leads to anemia. Its impact can sometimes be life-threatening. This disorder though inherited...


Please enter your comment!
Please enter your name here

Get in Touch

Trending Now

8 most effective remedies for Toenail Fungus

Do you have a toenail that is hard, discolored, disfigured, and falls off after some time? This kind of toenail is because of an...

Stroke or Cardiac arrest in the bathroom is frequent.

One of the studies has shown that there is a rapid increase in bathing death accidents. The results identified cardiovascular diseases as the leading...

The Pros and Cons of an Indoor and Outdoor Workout

When you think of working out, you probably think of hitting the gym. But what about exercising outdoors? Is there a benefit to getting...

Common myths and facts about HIV/AIDS

HIV and AIDS are already being used as an alternative to each other by many literate people, which has distorted its real difference. There...