Pancreatic cancer explained

Mr. Manohar Parrikar, a well known Indian Politician and the former Defence Minister of India, died of pancreatic cancer at the age of 63. Mr. Parrikar was undergoing treatment for a pancreatic ailment from October 2018, at AIIMS, Delhi, India.

Pancreatic cancer is one of the types of cancer-related to the pancreas in the body. It is very devastating and heartbreaking once someone diagnosed with cancer. A cancer diagnosis may affect their lives and the lives of loved ones also.

Moving ahead, we must understand the pancreas first.

  • Most people don’t know much about the pancreas. The pancreas is the endocrine gland which produces certain hormones like Insulin, Glucagon, and somatostatin along with several enzymes. The pancreas has exocrine as well as endocrine function.
  • The pancreas is located in the upper left abdomen behind the stomach. It is surrounded by other organs like the intestine, spleen, and liver. The pancreas is 6 to 10 inches long, banana-shaped, and spongy organ.

Pancreatic Cancer

Pancreatic Cancer refers to tumors that start in the cells of the pancreas. The cells grow in an unconditional manner and form the masses or tumors in the pancreas, instead of growing into healthy pancreatic tissues. These tumors may also spread to other parts of the body very speedily.

Pancreatic cancer is also known as pancreatic adenocarcinoma or pancreatic exocrine cancer. Symptoms of pancreatic cancer may include Jaundice, pain, and weight loss. Other than this, below symptoms also seen;

  • Pain in the upper abdomen that radiates to your back
  • Depression
  • Fatigue
  • Blood Clots
  • The onset of diabetes coupled with weight loss or loss of appetite
  • Dark Urine and light-colored stool

The symptoms may or may not be noticed still the cancer is in an advanced stage. If the signs and symptoms appear, they will be like symptoms of other illness.

Risk Factors

Having a risk factor does not mean that it will cause cancer or vice versa. The risk factors of pancreatic cancer may include;

  • Smoking
  • Obesity
  • Diabetes and its staging
  • Chronic inflammation of the pancreas (Pancreatitis)
  • The family history of pancreatic cancer
  • If having certain genetic or hereditary conditions.
  • Age factor. Older people after 65 are more at risk.

Diagnosis and Treatment options

Pancreatic cancer is difficult to diagnose and detect in the early stages. As the pancreas is hidden behind other organs such as the stomach, small intestine, gall bladder, and liver. In order to plan the treatment to the disease, it is important to diagnose and know the stage of it. Understand the stages of cancer, here.

National Cancer Institute recommends the following tests to be performed for the diagnosis;

  • Physical exam and history.
  • Blood chemistry studies where bilirubin content in blood is measured.
  • Tumor marker test
  • A magnetic Resonance imaging test
  • Abdominal and Endoscopic Ultrasound
  • Laparoscopy
  • Biopsy

There are different types of treatment options are available. Some treatments are standard, and some may be used in clinical trials.

  • Surgery
  • Radiation therapy
  • Chemotherapy
  • Other targeted therapy


It is recommended to live a healthy lifestyle applies to everyone, regardless of their genetic risk of pancreatic cancer.

  1. Do not smoke
  2. Use alcohol in moderation
  3. Maintain a healthy weight
  4. Choose a healthy nutrition
  5. Limit the exposure to chemicals at the workplace
  6. Consult a genetic counselor if you are having a family history of pancreatic cancer

Scientists are further planning to investigate to what extent the risk of pancreatic cancer can be reduced by several preventive measures. The lifestyle modification and performance of the preventive measures will be beneficial in the longer run.

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